Thermo Fisher Scientific CD1c Polyclonal Antibody
Thermo Fisher Scientific의 CD1c Polyclonal Antibody는 인간 CD1c 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 보관되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 75–135. Recombinant protein control fragment (Product #RP-110163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3092331 |
Product Specific Information
- Immunogen sequence:
NFSNEELSDL ELLFRFYLFG LTREIQDHAS QDYSKYPFEV QVKAGCELHS GKSPEGFFQV A - Antigen sequence identity:
Mouse 37%; Rat 38%
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to major histocompatibility complex (MHC) proteins, forming heterodimers with beta-2-microglobulin. CD1 proteins mediate the presentation of lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1. These members differ in cellular localization and lipid ligand specificity. The encoded protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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