Thermo Fisher Scientific GABRA4 Polyclonal Antibody
GABRA4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- PA5101597
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GABRA4 (Accession P48169), corresponding to amino acid residues A14–R64 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851031 |
Product Specific Information
Antibody detects endogenous levels of total GABRA4.
Target Information
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor.
At least 16 distinct subunits of GABA-A receptors have been identified.
This gene encodes subunit alpha-4, which is associated with autism etiology and may increase autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1.
Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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