Thermo Fisher Scientific GGH Polyclonal Antibody
Thermo Fisher Scientific의 GGH Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 토끼 유래 IgG 항체입니다. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적 저장(-20°C) 및 연구용에 최적화된 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GGH (Accession Q92820), corresponding to amino acid residues L255–T305 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851033 |
Product Specific Information
Antibody detects endogenous levels of total GGH.
Target Information
Gamma-Glutamyl hydrolase (GGH) is a homodimeric protein that catalyzes the cleavage of the gamma-glutamyl chain of folylpoly-gamma-glutamyl substrates and is a central enzyme in folyl and antifolyl poly-gamma-glutamate metabolism. The activities of the baculovirus-expressed enzyme and the enzyme from HL-60 cells were similar on methotrexate polyglutamates. GGH is expressed in a variety of human tumors and correlates with poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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