
Thermo Fisher Scientific STING/TMEM173 Polyclonal Antibody
STING/TMEM173 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 선천면역 신호전달 연구에 유용하며, 4°C에서 보관하고 Wet ice 조건으로 배송됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A305852Ax (2개 옵션)
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Amount: 15–20 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 329 and 379 of human Transmembrane protein 173 (STING, UniProt ID: Q86WV6-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
STING (Stimulator of Interferon Genes) is a 379-amino-acid signaling protein that plays a crucial role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferon (IFN-α and IFN-β) expression, establishing an antiviral state. STING may also function as a translocon influencing interferon induction and participates in apoptotic signaling via MHC-II association. It is typically localized to the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across most tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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