Thermo Fisher Scientific MFN2 Polyclonal Antibody
MFN2 단백항체로 인간, 생쥐, 랫트 시료에 반응하며 Western blot, ICC/IF, ELISA에 사용 가능. 미토콘드리아 융합 관련 단백질 검출에 적합. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol 저장 용액 제공.
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Thermo Fisher Scientific MFN2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 70–260 of human Mitofusin 2 (NP_055689.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913757 |
Product Specific Information
- Positive test controls: Raji, MCF7, 293T, Mouse brain, Rat brain
- Localization: Mitochondrion outer membrane, Multi-pass membrane protein
- Immunogen sequence:
TTEEQVLDVK GYLSKVRGIS EVLARRHMKV AFFGRTSNGK STVINAMLWD KVLPSGIGHT TNCFLRVEGT DGHEAFLLTE GSEEKRSAKT VNQLAHALHQ DKQLHAGSLV SVMWPNSKCP LLKDDLVLMD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKH FFHKVSERLS RPNIFILNNR W
Target Information
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in regulation of vascular smooth muscle cell proliferation and may play a role in obesity pathophysiology. Mutations cause Charcot-Marie-Tooth disease type 2A2 and hereditary motor and sensory neuropathy VI, both peripheral nervous system disorders. Defects are also associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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