Thermo Fisher Scientific MFN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-260 of human Mitofusin 2 (NP_0556891) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MFN2,uniProtId:O95140-1,ncbiNodeId:9606,antigenRange:70-260,antigenLength:757,antigenImageFileName:PA5-120185_MFN2_O95140-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120185_MFN2_O95140-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913757

Product Specific Information

Positive test controls include: Raji, MCF7, 293T, Mouse brain, Rat brain. The target is usually found in the following locations: Mitochondrion outer membrane, Multi-pass membrane protein.

Immunogen sequence: TTEEQVLDVK GYLSKVRGIS EVLARRHMKV AFFGRTSNGK STVINAMLWD KVLPSGIGHT TNCFLRVEGT DGHEAFLLTE GSEEKRSAKT VNQLAHALHQ DKQLHAGSLV SVMWPNSKCP LLKDDLVLMD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKH FFHKVSERLS RPNIFILNNR W

Target Information

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.