Thermo Fisher Scientific Human CDK1/cyclin A2, GST Tag Recombinant Protein

Thermo Fisher Scientific Human CDK1/cyclin A2, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
Do not store kinase diluted.
Properly stored at -80°C, guaranteed for 6 months from date of purchase.

Recombinant full-length human CDK1 and Cyclin A2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

Features:

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple and optimized use
• Multiple pack sizes available for convenience

Related Product:
LanthaScreen™ Eu Kinase Binding Assay

Protein Form: Recombinant
Gene Accession Numbers: CDK1 (NP_001777.1), Cyclin A2 (NP_001228.1)

Target Information

CDK1 (Cell Division Control protein 1) is essential for the completion of START, initiating mitosis. It acts as the catalytic subunit of the M-Phase Promoting Factor, inducing mitotic entry in eukaryotic cells.
Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves CDK1 signaling and delays apoptosis onset.
CDK inhibitor NU2058 shows therapeutic potential in androgen-independent prostate cancer.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.