Thermo Fisher Scientific CD8B1 Monoclonal Antibody (4C8)
인간 CD8B1 단백질을 인식하는 마우스 단클론 항체(클론 4C8)로, ELISA에 적합합니다. 친화 크로마토그래피로 정제되었으며, 보존제 없이 PBS(pH 7.4) 용액 형태로 제공됩니다. -20°C에서 보관하며, 반복 동결/해동은 피해야 합니다.
- 카탈로그번호
- H00000926-M07
- 판매단위
- pk
카탈로그
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Applications
ELISA (ELISA)
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C8 |
| Immunogen | CD8B1 (NP_004922, 23 a.a. ~131 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QQTPAYIKVQ TNKMVMLSCE AKISLSNMRI YWLRQRQAPS SDSHHEFLAL WDSAKGTIHG EEVEQEKIAV FRDASRFILN LTSVKPEDSG IYFCMIVGSP ELTFGKGTQ
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by antigen-presenting cells (APCs) in the context of class I MHC molecules. The functional coreceptor can be either a homodimer of two alpha chains or a heterodimer of one alpha and one beta chain. Both chains share significant homology with immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms, and multiple alternatively spliced transcript variants encoding distinct membrane-associated or secreted isoforms have been described. A pseudogene located on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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