Thermo Fisher Scientific CENPM Polyclonal Antibody
Human CENPM 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공됩니다. CENPM 단백질 연구 및 세포분열 관련 연구에 활용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CENPM. Recombinant protein control fragment (Product #RP-106704) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664922 |
Product Specific Information
Immunogen sequence:
TEESLRHVDAS FFLGKVCFLA TGAGRESHCS IHRHTVVKLA HTYQSPLLYC DLEVEG
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 79%
Target Information
The centromere is a specialized chromatin domain present throughout the cell cycle that acts as a platform for kinetochore assembly during mitosis. All active centromeres contain nucleosomes in which CENPA replaces histone H3. CENPM is an essential factor required for centromere assembly.
All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]). [Supplied by OMIM]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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