Thermo Fisher Scientific HKDC1 Polyclonal Antibody
Human HKDC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 포함. 암 관련 HKDC1 단백질 연구에 적합.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HKDC1 (aa 567–660) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642457 |
Product Specific Information
Immunogen sequence:
QGTGEELFDH IVQCIADFLD YMGLKGASLP LGFTFSFPCR QMSIDKGTLI GWTKGFKATD CEGEDVVDML REAIKRRNEF DLDIVAVVND TVGT
- Highest antigen sequence identity to orthologs:
- Mouse: 95%
- Rat: 79%
Target Information
HKDC1 (Hexokinase Domain Containing 1) is a cell-surface receptor belonging to the ErbB family of receptor tyrosine kinases. It binds ligands such as epidermal growth factor (EGF) and transforming growth factor alpha (TGFα), playing key roles in cellular proliferation, differentiation, motility, and survival.
Overexpression or mutation of HKDC1 has been associated with various cancers, including lung cancer and glioblastoma multiforme. The HKDC1vIII variant is frequently observed in glioblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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