Thermo Fisher Scientific Calpain 15 Polyclonal Antibody
Calpain 15 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. Human 시료 반응성. 항원 친화 크로마토그래피로 정제됨. PBS, 40% glycerol, 0.02% sodium azide 함유. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 15. Recombinant protein control fragment (Product #RP-89312). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639246 |
Product Specific Information
Immunogen sequence:
FLPVLNGVLP KPPAILGEPK GSCQEEAGPV RTAGLVATEP ARGQCEDKDE EEKEEQEEEE GAAEPRGGWA CPRCTLHNTP VASSCSVCGG PRRLSLPRIP PEALVVPE
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 76%
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific isoforms. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding different isoforms have been identified. Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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