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Thermo Fisher Scientific ITPKB Polyclonal Antibody
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ITPKB 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태, -20°C 보관.
- 카탈로그번호
- PA549796
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 02:18
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Thermo Fisher Scientific PA549796 ITPKB Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
630,500원VAT 포함 693,550원
Thermo Fisher Scientific · Thermo Fisher Scientific ITPKB Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human ITPKB (UniProt ID: P27987-1, antigen range: 189–208) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635249 |
Product Specific Information
This antibody detects endogenous levels of total ITPKB protein.
Target Information
Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) regulates intracellular calcium release. It is phosphorylated by inositol 1,4,5-trisphosphate 3-kinase (IP3K) to form inositol 1,3,4,5-tetrakisphosphate (Ins(1,4,5)P4), which may regulate calcium influx across the plasma membrane.
IP3K has three isoforms: IP3KA, IP3KB, and IP3KC.
- IP3KA: Expressed in rat brain and testis
- IP3KB: Expressed in rat lung, thymus, testis, brain, and heart
IP3K activity is stimulated by calmodulin and phosphorylation via cAMP-dependent protein kinase, protein kinase C, or calcium/calmodulin-dependent protein kinase II, mediating inositol phosphate signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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