Thermo Fisher Scientific ASGR1 Polyclonal Antibody
마우스 ASGPR1/ASGR1 단백질에 특이적인 Thermo Fisher Scientific의 폴리클로날 항체. ELISA 및 IHC(P) 등 다양한 응용에 적합. 보존제 무첨가로 고순도, 장기 보관 시 -20°C 저장 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Mouse ASGPR1/ASGR1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788534 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Mouse ASGPR1/ASGR1.
Target Information
The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) that mediates binding, internalization, and degradation of extracellular glycoproteins with exposed terminal galactose residues.
It is expressed on the surface of hepatocytes in a polar manner—present on sinusoidal and lateral plasma membranes but not on the bile canalicular membrane.
The mammalian hepatic ASGPR mediates endocytosis and degradation of serum proteins lacking terminal sialic residues.
The rat ASGPR consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2, and RHL-3.
The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR and is cross-reactive with human ASGPR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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