Thermo Fisher Scientific CD4 Polyclonal Antibody, Biotin
CD4 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, Western blot, ELISA, IP에 사용 가능. 인간, 마우스, 비인간 영장류 반응성. 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 270–320 on human CD4 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but may also be found in monocytes, macrophages, and dendritic cells. It is expressed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 assists in T-cell activation through interaction with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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