
Thermo Fisher Scientific Ubiquitin Polyclonal Antibody
Thermo Fisher Scientific의 Ubiquitin Polyclonal Antibody는 인간, 마우스, 랫 등 다양한 종에 반응하는 다클론 항체입니다. Western blot 및 IHC(파라핀) 실험에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 보관하며 연구용으로 사용됩니다.
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Thermo Fisher Scientific Ubiquitin Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | All, Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–32 amino acids from the N-terminal region of human Ubiquitin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Size-exclusion - Dialysis, Ammonium sulfate precipitation, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2180700 |
Product Specific Information
This antibody is predicted to react with bovine, chicken, canine, hamster, mouse, porcine, non-human primate, rat, rabbit, and Xenopus based on sequence homology.
Target Information
Ubiquitin is a highly conserved protein that plays a major role in targeting cellular proteins for degradation by the 26S proteasome. It is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein.
The gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a.
Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome.
Similarly, ribosomal protein L40 and S30 are synthesized as fusion proteins with ubiquitin or ubiquitin-like proteins. Multiple alternatively spliced transcript variants encoding the same proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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