Thermo Fisher Scientific ACY1 Monoclonal Antibody (OTI2B5), Biotin, TrueMAB
Thermo Fisher Scientific의 ACY1 Monoclonal Antibody (OTI2B5)은 인간 ACY1 단백질을 인식하는 mouse IgG1 형 단클론 항체로, Biotin으로 표지되어 있습니다. ELISA 및 Luminex 분석에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B5 |
| Immunogen | Full length human recombinant protein of human ACY1 produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group. It is involved in the catabolism and salvage of acylated amino acids.
This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), where expression is often reduced or undetectable.
Mutations in ACY1 cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids.
Alternative splicing results in multiple transcript variants, and read-through transcription exists between ACY1 and the upstream ABHD14A gene. A related pseudogene is found on chromosome 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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