Thermo Fisher Scientific UBE2E1 Polyclonal Antibody
Human UBE2E1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20~1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 단백질 유비퀴틴화 연구에 적합.
- 카탈로그번호
- PA556476
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBE2E1. Recombinant protein control fragment (Product # RP-102081) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649175 |
Product Specific Information
Immunogen sequence:
LLSTSAKRIQ KELADITLDP PPNCSAGPKG DNIYEWRSTI LGPPGSVYEG GVFFLDITFT PEYPFKPPKV TFRTRIYHCN INSQGVICLD ILKDNWSPAL TIS
Antigen identity:
Highest sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins and mediates the selective degradation of short-lived and abnormal proteins.
The modification of proteins with ubiquitin is a crucial cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves three classes of enzymes:
- E1 – Ubiquitin-activating enzymes
- E2 – Ubiquitin-conjugating enzymes
- E3 – Ubiquitin-protein ligases
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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