Thermo Fisher Scientific KIRREL Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KIRREL

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643122

Product Specific Information

Immunogen sequence: VTLSIEPQTV QEGERVVFTC QATANPEILG YRWAKGGFLI EDAHESRYET NVDYSFFTEP VSCEVHNKVG STNVSTLVNV HFAPRIVVDP KPTTTDIGSD VTLTCVWVGN PPLTLTWTKK DSNMVLSNSN QLLLKSVTQA DA

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.