Thermo Fisher Scientific TSC22D4 Polyclonal Antibody
Thermo Fisher Scientific의 TSC22D4 Polyclonal Antibody는 마우스 TSC22D4 단백질을 인식하는 토끼 IgG 항체입니다. WB와 IHC에 사용 가능하며, Protein A로 정제된 액상 형태입니다. PBS 버퍼에 2% sucrose와 0.09% sodium azide를 포함하며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5.0 µg/mL | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of mouse TSC22D4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2692296 |
Product Specific Information
This target displays homology in the following species:
Cow: 79%; Dog: 77%; Guinea Pig: 92%; Horse: 86%; Human: 92%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%
Target Information
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1.
Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systemic glucose homeostasis and insulin sensitivity via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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