Thermo Fisher Scientific TSC22D4 Polyclonal Antibody
TSC22D4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Mouse에 반응하며, PBS와 2% sucrose buffer에 보관됩니다. Affinity chromatography로 정제되었으며, -20°C에서 보관 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse TSC22D4 (aa 241–290) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689378 |
Product Specific Information
This target displays homology in the following species:
- Cow: 90%
- Guinea Pig: 90%
- Human: 90%
- Mouse: 100%
- Rabbit: 90%
- Rat: 100%
Target Information
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1.
Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systemic glucose homeostasis and insulin sensitivity via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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