Thermo Fisher Scientific SOD3 Monoclonal Antibody (4GG11G6), PE
SOD3 단백질을 인식하는 PE 결합 단클론 항체로, Western blot, IHC, ICC/IF, ELISA에 적합합니다. Human, Mouse, Rat, Guinea pig 반응성이 있으며, 단백질 G 정제 및 보존제 무첨가 상태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4GG11G6 |
| Immunogen | Human extracellular SOD purified from aortas |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931680 |
Additional Formats
Product Specific Information
1 µg/mL of MA5-45226 was sufficient for detection of EC-SOD in 20 µg of human cartilage lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects extracellular SOD approximately 35 kDa.
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells such as testis, thymus, fetal liver, and carcinomas. The protein localizes to the nucleus and promotes the stability and nuclear accumulation of transcriptionally active p53. It phosphorylates Thr18 of p53, reducing p53 ubiquitination, and may regulate cell proliferation. It also phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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