Thermo Fisher Scientific FBXO11 Monoclonal Antibody (4C12)
FBXO11 단백질을 인식하는 Mouse monoclonal antibody(클론 4C12). WB, IHC, ICC, ELISA에 적합하며 인간 시료에 반응. PBS buffer에 보관되며, 보존제 미함유. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C12 |
| Immunogen | FBXO11 (NP_079409, 744–843 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KAVSRGQCLY KISSYTSYPM HDFYRCHTCN TTDRNAICVN CIKKCHQGHD VEFIRHDRFF CDCGAGTLSN PCTLAGEPTH DTDTLYDSAP PIESNTLQHN
Target Information
FBXO11 is a member of the F-box protein family characterized by an approximately 40 amino acid F-box motif. These proteins form one of the four subunits of the ubiquitin protein ligase complex SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:
- Fbws containing WD-40 domains
- Fbls containing leucine-rich repeats
- Fbxs containing other protein-protein interaction modules or no recognizable motifs
FBXO11 belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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