Thermo Fisher Scientific MYLK Polyclonal Antibody
MYLK 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC/IF, Flow Cytometry 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액 포함. 연구용으로만 사용.
- 카탈로그번호
- PA586032
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:10–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYLK amino acids 230–470 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802833 |
Target Information
MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in contractile activity through myosin–actin interaction. It plays a key role in smooth muscle contraction, vascular permeability, and tissue edema formation. In the nervous system, MYLK regulates astrocytic process growth and neurotransmitter release at synapses. It is involved in fibroblast apoptosis signaling and is expressed in a wide range of adult and fetal tissues. The protein includes one fibronectin type III domain and nine immunoglobulin-like C2-type domains. MYLK expression is likely down-regulated by phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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