Thermo Fisher Scientific Rat IL-13 Recombinant Protein
Rat IL-13 재조합 단백질로 면역 및 염증 반응 연구에 적합. E. coli 발현 시스템 기반의 carrier-free 액상 형태. ELISA, Western blot 등 다양한 어세이에 사용 가능. 알레르기 및 면역 조절 메커니즘 분석에 활용.
- 카테고리
- Protein
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | E. coli |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Carrier-Free
Stock solutions can be prepared at 50–100 µg/mL in appropriate sterile buffer. Carrier proteins such as 0.2–1% BSA or HSA can be added when preparing the stock solution.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. It regulates inflammatory and immune responses by down-regulating macrophage activity, inhibiting pro-inflammatory cytokine and chemokine production. IL-13 plays a role in allergen-induced asthma through mechanisms independent of IgE and eosinophils.
Additionally, IL-13 regulates B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The genes encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with IL-13 located near IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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