Thermo Fisher Scientific Rat GM-CSF Recombinant Protein

Thermo Fisher Scientific Rat GM-CSF Recombinant Protein

Applications

• Western Blot (WB): Assay-dependent
• ELISA (ELISA): Assay-dependent
• Control (Ctrl): Assay-dependent

Product Specifications

Product Specific Information

Carrier-Free
Stock solutions can also be prepared at 50–100 µg/mL in appropriate sterile buffer. Carrier protein such as 0.2–1% BSA or HSA can be added when preparing the stock solution.

Target Information

The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space.
This gene is located in a cluster of related genes at chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia.
Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation.
Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.