ELK Biotechnology Histone H3 (Acetyl Lys123) rabbit pAb
Histone H3 (Acetyl Lys123)에 특이적인 토끼 다클론 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 핵 및 염색체 단백질 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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Histone H3 (Acetyl Lys123) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Acetyl Lys123) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5; H3k123AC |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications. |
| Immunogen | Synthesized acetyl-peptide derived from the C-terminal region of human Histone H3 around the acetylation site of K123. |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021, 440093 |
| Human Swiss-Prot No. | P68431, Q71DI3, P84243, Q6NXT2 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for forming the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6p22-p21.3.
(Information provided by RefSeq, Aug 2015)
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