ELK Biotechnology Tubulin α (Acetyl Lys40) rabbit pAb
Tubulin α (Acetyl Lys40) rabbit polyclonal antibody로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC, IF, ELISA에 적합하며, 세포질 및 세포골격 내 α-튜불린 검출에 유용합니다. 합성 Acetyl-peptide를 면역원으로 제작되어 높은 특이성과 재현성을 제공합니다.
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제품명
Tubulin α (Acetyl Lys40) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | TUBA1A; TUBA3; Tubulin alpha-1A chain; Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain; TUBA1B; Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain; TUBA1C; TUBA6; Tubulin alpha-6 chain; TUBA3C; TUBA2; TUBA3D; Tubulin alpha-3C/D chain; Alpha-tubulin 2; Alpha-tubulin 3C/D; Tubulin alpha-2 chain; TUBA4A; TUBA1; Tubulin alpha-4A chain; Alpha-tubulin 1; Testis-specific alpha-tubulin |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized Acetyl-peptide derived from human TUBA1A around the Acetylation site of Lys40 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C (1 year) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| GeneID (Human) | 7846 |
| Human Swiss-Prot No | Q71U36 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which consists of six distinct families. Genes from the alpha, beta, and gamma tubulin families are found in all eukaryotes.
Alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in microtubule nucleation. Multiple alpha and beta tubulin genes are highly conserved among species.
This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 genes. Northern blotting studies have shown that gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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