ELK Biotechnology CRM1 (Acetyl Lys568) rabbit pAb
CRM1 (Acetyl Lys568) rabbit pAb는 인간 CRM1 단백질의 K568 아세틸화 부위를 인식하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 핵과 세포질 내 CRM1 단백질 연구에 유용하며, 높은 특이성과 안정적인 보관성을 제공합니다.
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제품명
CRM1 (Acetyl Lys568) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized acetyl-peptide derived from the internal region of human CRM1 around the acetylation site of K568 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 125 kD |
| GeneID (Human) | 7514 |
| Human Swiss-Prot No | O14980 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.
배경 정보
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
[provided by RefSeq, Jan 2015]
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