ELK Biotechnology Cleaved-Integrin α5 LC (E895) rabbit pAb
Cleaved-Integrin α5 LC (E895) rabbit pAb는 인간 ITGA5 유래 펩타이드로부터 제작된 폴리클로날 항체입니다. WB와 ELISA에 사용 가능하며, 세포막 및 focal adhesion에서 Integrin α5 단백질 검출에 적합합니다. -20°C에서 1년 보관 가능합니다.
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Cleaved-Integrin α5 LC (E895) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-Integrin α5 LC (E895) rabbit pAb |
| Alternative Names | ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ITGA5 (AA range: 876–925) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 18 kD |
| Gene ID (Human) | 3678 |
| Human Swiss-Prot No. | P08648 |
| Cellular Localization | Membrane; Single-pass type I membrane protein; Cell junction; Focal adhesion; Cell surface |
| Species Reactivity | Human; Rat; Mouse |
Background
Integrin subunit alpha 5 (ITGA5) Homo sapiens
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling.
The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor.
This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients.
Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
(Provided by RefSeq, Oct 2015)
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