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ELK Biotechnology Cleaved-PARP-1 (G215) rabbit pAb
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ELK Biotechnology Cleaved-PARP-1 (G215) rabbit pAb

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Cleaved-PARP-1 (G215) rabbit pAb는 인간 PARP 유래 합성 펩타이드로 제작된 폴리클로날 항체입니다. Western blot과 ELISA에 적합하며, 핵 내 DNA 손상 부위에 특이적으로 결합합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.

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pk
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ELK Biotechnology ES1052-100UL Cleaved-PARP-1 (G215) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1052-50UL Cleaved-PARP-1 (G215) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Cleaved-PARP-1 (G215) rabbit pAb

Cleaved-PARP-1 (G215) rabbit pAb

제품 정보

항목 내용
Product name Cleaved-PARP-1 (G215) rabbit pAb
Alternative Names PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Applications WB; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
ELISA: 1/5000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human PARP (AA range: 196–245)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 89 kD
GeneID (Human) 142
Human Swiss-Prot No P09874
Cellular Localization Nucleus; Nucleolus; Chromosome; Localizes to sites of DNA damage
Species Reactivity Human; Mouse; Rat

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is DNA-dependent and is involved in the regulation of key cellular processes such as differentiation, proliferation, and tumor transformation, as well as in the recovery of cells from DNA damage. Mutations in this enzyme may be associated with Fanconi anemia and type I diabetes pathophysiology. (RefSeq, Jul 2008)

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