ELK Biotechnology Cleaved-MMP-15 (Y132) rabbit pAb
Cleaved-MMP-15 (Y132) rabbit pAb은 인간 및 원숭이 시료에 반응하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 세포막 단백질 MMP-15를 인식하며, 암 진행 및 세포외기질 분해 연구에 활용됩니다. -20°C에서 1년간 안정 저장 가능합니다.
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Cleaved-MMP-15 (Y132) rabbit pAb
제품 개요
Cleaved-MMP-15 (Y132) rabbit pAb은 인간 MMP15 유래 합성 펩타이드(AA 113-162)를 면역원으로 제작된 폴리클로날 항체입니다. 세포막에 위치한 단백질을 인식하며, 암 진행 및 세포외기질 분해 관련 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-MMP-15 (Y132) rabbit pAb |
| Alternative Names | MMP15; Matrix metalloproteinase-15; MMP-15; Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human MMP15 (AA range: 113-162) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 61 kD |
| Gene ID (Human) | 4324 |
| Human Swiss-Prot No | P51511 |
| Cellular Localization | Membrane; Single-pass type I membrane protein; Extracellular side |
| Species Reactivity | Human; Monkey |
Background
This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain, suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016]
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