ELK Biotechnology Caspase-14 rabbit pAb
Caspase-14 rabbit pAb는 인간, 랫, 마우스에 반응하는 다클론 항체로, 세포자멸사 연구에 적합합니다. WB와 ELISA에 사용 가능하며, 고순도 IgG 형태로 제공됩니다. 세포질과 핵에서 발현되는 Caspase-14 단백질 검출에 유용합니다.
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Caspase-14 rabbit pAb
공급업체: ELK Biotechnology
제품 개요
Caspase-14 rabbit pAb는 세포자멸사(apoptosis) 관련 단백질인 Caspase-14를 검출하기 위한 다클론 항체입니다. 인간, 랫, 마우스 시료에서 반응하며, Western Blot 및 ELISA에 적합합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product Name | Caspase-14 rabbit pAb |
| Alternative Names | CASP14; Caspase-14; CASP-14 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from Caspase-14 (AA range: 110–190) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 27 kD |
| GeneID (Human) | 23581 |
| Human Swiss-Prot No | P31944 |
| Cellular Localization | Cytoplasm, Nucleus |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis-inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. (provided by RefSeq, Jul 2008)
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