ELK Biotechnology Cleaved-Caspase-6 p18 (D179) rabbit pAb
Cleaved-Caspase-6 p18 (D179) rabbit polyclonal antibody로, apoptosis 연구에 적합. WB, IHC, IF, ELISA 등 다양한 응용 가능. 인간 Caspase-6 유래 펩타이드로 제작. 세포질 및 핵에서 발현 검출. 고순도 IgG, -20°C에서 1년 보관.
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Cleaved-Caspase-6 p18 (D179) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-Caspase-6 p18 (D179) rabbit pAb |
| Alternative Names | CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 6 (AA range: 130-179) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 20 + 35 kD |
| GeneID (Human) | 839 |
| Human Swiss-Prot No | P55212 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Rat |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8, and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. (provided by RefSeq, Oct 2015)
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