Thermo Fisher Scientific Caveolin 1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Keep as a concentrated solution.
• Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%).
• Positive Control: A431, H1299, HeLa, A549, A7, Mouse lung.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Caveolin-1 (CAV1) is a scaffolding protein within caveolar membranes. It interacts directly with G-protein alpha subunits and regulates their activity. Caveolin-1 also participates in co-stimulatory signaling essential for T-cell receptor (TCR)-mediated T-cell activation. It can bind with DPP4 and induce T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations in the CAV1 gene are associated with congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts and neurodegeneration syndrome.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.