Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody
Human SDCCAG8 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human SDCCAG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636743 |
Product Specific Information
This antibody detects endogenous levels of total SDCCAG8 protein.
Target Information
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085, or NY-CO-8, is a 713 amino acid cytoplasmic protein expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, and renal cancer tumors.
Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder characterized by dysplasia or degeneration of the kidney, retina, and cerebellum.
SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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