Thermo Fisher Scientific Zyxin Polyclonal Antibody
Human Zyxin 단백질을 인식하는 Goat 유래 Polyclonal 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태(0.5 mg/mL)로 제공됩니다. -20°C 보관, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Zyxin Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QQREKPRVQEKQH) corresponding to internal amino acids of ZYX (aa 318–331) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983130 |
Product Specific Information
- Predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
Zyxin is involved in focal adhesions, actin-rich structures that enable cells to adhere to the extracellular matrix and participate in signal transduction. It is a zinc-binding phosphoprotein concentrated at focal adhesions and along the actin cytoskeleton.
Zyxin contains an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of signaling proteins, while LIM domains are involved in protein-protein binding. Zyxin may act as a messenger in adhesion-stimulated gene expression and modulate actin bundle organization.
Alternative splicing results in multiple transcript variants encoding the same isoform.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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