Thermo Fisher Scientific IGSF10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human IGSF10 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IGSF10,uniProtId:Q6WRI0-1,ncbiNodeId:9606,antigenRange:456-601,antigenLength:2623,antigenImageFileName:PA5-53009_IGSF10_Q6WRI0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53009_IGSF10_Q6WRI0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642670

Product Specific Information

Immunogen sequence: AQITLPRAEM RPVKHKWTMI SRDNNTKLEH TVLVGGTVGL NCPGQGDPTP HVDWLLADGS KVRAPYVSED GRILIDKSGK LELQMADSFD TGVYHCISSN YDDADILTYR ITVVEPLVEA YQENGIHHTV FIGETLDLPC HSTGIP

Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 75%.

Target Information

Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.