Thermo Fisher Scientific ARHGEF1 Polyclonal Antibody
ARHGEF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC 및 ICC/IF 실험에 적합하며, 높은 특이성과 재현성을 제공. 액상 형태로 4°C 단기, -20°C 장기 보관 가능. 연구용으로만 사용.
- 카탈로그번호
- PA553011
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARHGEF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638159 |
Product Specific Information
Immunogen sequence:
YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG LSSILDAARW NRGEPQVPDF RHLKAEVDAE KPGATDRKGG VGMPSRDRNI GAPGQDTPGV SLHPLSLDSP DREP
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 83%
Target Information
The Ras superfamily of GTPases, subdivided into Ras, Rho/Rac, Sar, Rab, ARF, and Ran subfamilies, controls multiple aspects of cell function such as cytoskeletal rearrangement, nuclear signaling, and cell growth. These GTPases act as regulated switches, toggling between an active GTP-bound and inactive GDP-bound form. Activation is catalyzed by guanine nucleotide exchange factors (GEFs).
Dbl-related proteins form a large family of structurally related molecules that catalyze GEF activity for specific members of the Ras family. Examples include FGD1, Lsc, RhoGEF p115, Lfc, Lbc, and Brx. Lsc, Lbc, and Lfc share sequence homology and show exchange activity toward Rho family GTPases. RhoGEF p115 catalyzes GEF activity for Rho but not Rac, Cdc42, or Ras GTPases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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