Thermo Fisher Scientific CD14 Monoclonal Antibody (TuK4), PerCP
인간 CD14 항원을 인식하는 마우스 단클론 항체로 PerCP 형광체로 표지되어 있습니다. 유세포 분석(Flow Cytometry)에 적합하며, 488 nm 레이저로 여기됩니다. 4°C 암소 보관이 필요하며, 다양한 포맷으로도 제공됩니다.
- 카탈로그번호
- MHCD1431
- 판매단위
- pk
카탈로그
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Applications
- Flow Cytometry (Flow): Assay-dependent
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TuK4 |
| Immunogen | Human CD14 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA, sucrose |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10374157 |
Additional Formats
- Unconjugated
- Alexa Fluor 647
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- Biotin
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Cyanine5.5
- PE-Texas Red
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Custom conjugation available
Product Specific Information
PerCP conjugates are excited by the 488 nm line of the argon-ion laser and have a large Stokes shift, providing minimal spectral overlap into the R-PE (phycoerythrin) channel.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein constitutively expressed on mature monocytes, macrophages, and neutrophils. It functions as a lipopolysaccharide (LPS) receptor and exists in both membrane-bound and soluble forms. CD14 interacts with LPS-binding protein (LBP) and plays a role in immune response modulation, apoptosis recognition, and inflammatory processes. Alternative splicing produces multiple transcript variants encoding the same isoform. CD14 dysfunction has been linked to mycobacterium chelonae infection and croup.
Analyte Specific Reagent
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