Thermo Fisher Scientific N-WASP Polyclonal Antibody
N-WASP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WASL (Accession O00401), corresponding to amino acid residues E231–P281 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852031 |
Product Specific Information
This antibody detects endogenous levels of total N-WASP.
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share a similar domain structure and are involved in transducing signals from cell surface receptors to the actin cytoskeleton. These proteins interact with multiple partners and are regulated by various stimuli. N-WASP (encoded by the WASL gene) is a homolog of WAS protein, ubiquitously expressed with the highest levels in neural tissues. It binds directly to Cdc42 and induces the formation of long actin microspikes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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