Thermo Fisher Scientific DYNLT1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Product Specifications

Target Information

DYNLT1 acts as a non-catalytic accessory component of the cytoplasmic dynein 1 complex, contributing to the linkage between dynein, cargos, and adapter proteins that regulate dynein function.
Cytoplasmic dynein 1 functions as a motor for intracellular retrograde transport of vesicles and organelles along microtubules.
DYNLT1 is involved in:

• Apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia
• Intracellular targeting of D-type retrovirus gag polyproteins
• Neuronal morphogenesis and regulation of the actin cytoskeleton via Rac1 activity
• Regulation of neurogenesis by inhibiting neuron formation from precursor cells during cortical development

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.