Thermo Fisher Scientific DYNC1H1 Polyclonal Antibody
DYNC1H1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat 시료에 반응. 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human DYNC1H1 (amino acids 2094–2117, UniProt ID: Q14204-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691896 |
Product Specific Information
Predicted to react with Human and Rat samples.
Target Information
ZEB2, initially identified as Smad interacting-protein 1, is a nuclear DNA-binding transcriptional repressor that interacts with activated SMADs. Similar to ZEB1, ZEB2 inhibits E-cadherin transcription and induces epithelial-mesenchymal transition (EMT), a key process in cell migration during embryonic development and wound healing. ZEB2 can also protect cells from DNA damage-induced apoptosis, potentially contributing to tumor progression. It is often observed in the cytoplasm of various cancer tissues, suggesting regulated localization in normal and tumor cells. Mutations in ZEB2 are associated with Hirschsprung disease/Mowat-Wilson syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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