Thermo Fisher Scientific Angiotensinogen Monoclonal Antibody (754438)
마우스 및 랫트 반응성을 가진 단클론 항체로, Angiotensinogen 단백질 검출에 적합합니다. Western blot과 동결 조직 면역조직화학(IHC(F))에 사용 가능하며, 단백질 A/G로 정제된 동결건조 형태입니다. 연구용으로 혈압 조절 관련 단백질 분석에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 8–25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 754438 |
| Immunogen | CHO-derived recombinant mouse Serpin A8/Angiotensinogen Asp25–Val477 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609480 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
The protein encoded by AGT (angiotensinogen precursor) is expressed in the liver and cleaved by renin when blood pressure drops. The resulting angiotensin I is further processed by angiotensin-converting enzyme (ACE) to produce angiotensin II, a key regulator of blood pressure.
Mutations in this gene are linked to essential hypertension, renal tubular dysgenesis, atrial fibrillation, and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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