Thermo Fisher Scientific Cathepsin C Polyclonal Antibody
Cathepsin C 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. 면역세포 내 단백질 분해 연구에 적합하며, ICC/IF 실험에서 1:50~1:200 희석으로 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human CTSC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720106 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
Cathepsin C, also known as dipeptidyl aminopeptidase I (DPPI), is a tetrameric lysosomal cysteine peptidase belonging to the papain family. It participates in intracellular protein degradation and processing of protein precursors, contributing to cell growth, neuraminidase activation, and platelet factor XIII activation.
Cathepsin C shares homology with other lysosomal cysteine proteinases such as cathepsin B, H, and L. It sequentially removes dipeptides from the amino terminus and requires chloride ions and thiols for full enzymatic activity.
The protein is expressed in various tissues, with highest levels in spleen, kidney, cytotoxic lymphocytes, and myeloid cells, localizing to the secretory granule compartment. It is synthesized as a proenzyme and processed into two chains that form the mature enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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