Thermo Fisher Scientific GANAB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_0012651231) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GANAB,uniProtId:Q14697-1,ncbiNodeId:9606,antigenRange:1-260,antigenLength:944,antigenImageFileName:PA5-89484_GANAB_Q14697-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89484_GANAB_Q14697-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.48 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805600

Product Specific Information

Immunogen sequence: MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE TPQTDVRWMS; Positive Samples: U-87MG, Raji, HepG2, HeLa, Mouse brain, Mouse liver, Rat brain; Cellular Location: Endoplasmic reticulum, Golgi apparatus, Melanosome

Target Information

This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.