Thermo Fisher Scientific PLA2G7 Polyclonal Antibody
Rabbit polyclonal antibody targeting PLA2G7 for human and mouse samples. Validated in WB and ELISA applications. Recombinant immunogen ensures high specificity. Supplied in liquid form with PBS/glycerol buffer for stable storage at -20°C. For research ...
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Thermo Fisher Scientific PLA2G7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 51–240 of human PLA2G7 (NP_0050753) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805604 |
Product Specific Information
- Immunogen sequence: FGQTKIPRGN GPYSVGCTDL MFDHTNKGTF LRLYYPSQDN DRLDTLWIPN KEYFWGLSKF LGTHWLMGNI LRLLFGSMTT PANWNSPLRP GEKYPLVVFS HGLGAFRTLY SAIGIDLASH GFIVAAVEHR DRSASATYYF KDQSAAEIGD KSWLYLRTLK QEEETHIRNE QVRQRAKECS QALSLILDID
- Positive Samples: Jurkat, U937, Mouse serum, Rat serum
- Cellular Location: Extracellular space
Target Information
Platelet Activating Factor (PAF) is a biologically active phospholipid that exerts proinflammatory activities via G-protein-coupled receptors on platelets, neutrophils, and monocytes.
Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by hydrolyzing the sn2 ester bond, converting PAF to inactive lyso-PAF.
PAF-AH also interacts with LDL particles to hydrolyze oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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