Thermo Fisher Scientific GM2A Monoclonal Antibody (2C8)
인간 GM2A 단백질을 인식하는 마우스 단클론 항체로, ELISA에 적합합니다. GST 태그가 포함된 부분 재조합 단백질로부터 유래하였으며, 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 용액 형태로 제공되며 방부제는 포함되지 않습니다.
- 카탈로그번호
- H00002760-M02
- 판매단위
- pk
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Applications
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C8 |
| Immunogen | GM2A (NP_000396.2, 94 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
WIKIPCTDYI GSCTFEHFCD VLDMLIPTGE PCPEPLRTYG LPCHCPFKEG TYSLPKSEFV VPDLELPSWL TTGNYRIESV LSSSGKRLGC IKIAASLKGI
Target Information
This gene encodes a small glycolipid transport protein which acts as a substrate-specific cofactor for the lysosomal enzyme beta-hexosaminidase A.
Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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