Thermo Fisher Scientific GLUD2 Monoclonal Antibody (3C2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3C2

Immunogen

GLUD2 (AAH05111.1, 1 a.a. approximately 264 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GLUD2,uniProtId:P49448-1,ncbiNodeId:9606,antigenRange:1-558,antigenLength:558,antigenImageFileName:H00002747-M01A_GLUD2_P49448-1_House_mouse.svg,antigenImageFileNamePDP:H00002747-M01A_GLUD2_P49448-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MTPGFRDKTF VVQGFGNVGL HSMRYLHRFG AKCIAVGESD GSIWNPDGID PKELEDFKLQ HGSILGFPKA KPYEGSILEV DCDILIPAAT EKQLTKSNAP RVKAKIIAEG ANGPTTPEAD KIFLERNILV IPDLYLNAGG VTVSYFEWLK NLNHVSYGRL TFKYERDSNY HLLLSVQESL ERKFGKHGGT IPIVPTAEFQ DSISGASEKD IVHSALAYTM ERSARQIMHT AMKYNLGLDL RTAAYVNAIE KVFKVYSEAG VTFT

Target Information

Glutamate dehydrogenase 2, Glud2, is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. Diseases associated with GLUD2 include Parkinson Disease, Late-Onset and Hyperinsulinemic Hypoglycemia, Familial, 6. Among its related pathways are GABA shunt and Carbon metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.