Thermo Fisher Scientific UHRF2 Polyclonal Antibody
Thermo Fisher Scientific의 UHRF2 Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하는 Rabbit IgG 항체입니다. Western Blot 및 ELISA에 적합하며, 세포 주기 조절 관련 연구에 활용됩니다. 고순도 Affinity Chromatography로 정제된 액상 형태로, 안정적인 장기 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 76–359 of mouse Uhrf2 (NP_659122.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855958 |
Product Specific Information
Immunogen sequence:
DSSLPSTSKQ NDAQVKPSSH NPPKVKKTAR GGSSSQPSTS ARTCLIDPGF GLYKVNELVD ARDVGLGAWF EAHIHSVTRA SDGHSRGKTP LKNGSSYKRT NGNVNHNSKE NTNKLDNVPS TSNSDSVAAD EDVIYHIEYD EYPESGILEM NVKDLRPRAR TILKWNELNV GDVVMVNYNV ENPGKRGFWY DAEITTLKTI SRTKKEVRVK VFLGGSEGTL NDCRVMSVDE IFKIEKPGAH PISFADGKFL RKNDPECDLC GGDPDKTCHM CSCHKCGEKR DPNM
Target Information
This gene encodes a nuclear protein involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.
It contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain — several of which are essential for the regulation of cell proliferation.
This protein may also participate in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants, some of which are non-protein coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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