Thermo Fisher Scientific UGT1A4 Polyclonal Antibody
UGT1A4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제된 액상 제품입니다. 연구용으로 사용되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human UGT1A4 (NP_0090511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806226 |
Product Specific Information
- Immunogen sequence:
MARGLQVPLP RLATGLLLLL SVQPWAESGK VLVVPTDGSP WLSMREALRE LHARGHQAVV LTPEVNMHIK EEKFFTLTAY AVPWTQKEFD RVTLGYTQGF - Positive Samples: Mouse liver, Mouse stomach, Rat liver
- Cellular Location: Endoplasmic reticulum membrane, Microsome, Single-pass membrane protein
Target Information
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites.
The gene locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are pseudogenes, and nine functional exons may be spliced to the four common exons, generating proteins with different N-termini and identical C-termini.
Each first exon encodes the substrate binding site and is regulated by its own promoter. This enzyme exhibits glucuronidase activity towards bilirubin and is more active on amines, steroids, and sapogenins.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-90760_UGT1A4_P22310-1_Rabbit.svg
- PA5-90760_UGT1A4_P22310-1_Rabbit_PDP.jpeg
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