Thermo Fisher Scientific TPCN1 Polyclonal Antibody
Rabbit polyclonal antibody against TPCN1 for WB and ELISA applications. Reacts with mouse and rat. High purity via affinity chromatography, supplied in PBS with glycerol. Suitable for research use in endosomal and lysosomal membrane protein studies.
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Thermo Fisher Scientific TPCN1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 692–816 of human TPCN1 (NP_0603712) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806224 |
Product Specific Information
- Immunogen sequence: FRMNYSRKNQ DSEVDGGITL EKEISKEELV AVLELYREAR GASSDVTRLL ETLSQMERYQ QHSMVFLGRR SRTKSDLSLK MYQEEIQEWY EEHAREQEQQ RQLSSSAAPA AQQPPGSRQR SQTVT
- Positive Samples: Rat lung
- Cellular Location: Endosome membrane, Lysosome membrane, Multi-pass membrane protein
Target Information
TPCN1 may function as one of the major voltage-gated Ca²⁺ channels (VDCC) across the plasma membrane. Voltage-gated Ca²⁺ and Na⁺ channels have four homologous domains, each containing six transmembrane segments (S1–S6). TPCN1 is similar to these channels but has only two domains containing S1–S6 (Ishibashi et al., 2000).
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-90758_TPCN1_Q9ULQ1-1_Rabbit.svg, PA5-90758_TPCN1_Q9ULQ1-1_Rabbit_PDP.jpeg)
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